Jennifer Rucci

New Developments in Menopausal Treatments

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Study finds antidepressant as effective as hormone replacement in menopausal symptoms.

A recent study in JAMA headed by Hadine Joffe, MD, an associate professor of psychiatry at Harvard Medical School, was the first trial comparing an antidepressant to estrogen replacement for improvement of menopausal symptoms.

The researchers looked at symptoms such as hot flashes and night sweats in menopausal women. The study compared groups taking the gold standard of estradiol (most common used form of hormone replacement) and a common antidepressant venlafaxine (also known as Effexor). The results showed comparable effects on these menopausal symptoms and suggest an evidence based approach to using antidepressants for this indication.

This is especially important as many groups of women can not, or chose not to, take hormone replacements. Having an alternative can improve the quality of life for many women.

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